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產(chǎn)品名稱：Anti-AT2R抗體
產(chǎn)品型號：Anti-AT2R
產(chǎn)品廠商：KALANG
產(chǎn)品文檔：

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簡單介紹：

Anti-AT2R抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-AT2R抗體用于**組化實驗,WB實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。

詳情介紹：

Rabbit Anti-AT2R

Cat. Number:

KL-0438R

Quantity size:

0.2ml

Concentration:

Anti-AT2R抗體1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Anti-AT2R抗體Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC?is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites.

Also known as:

Anti-AT2R抗體AG2S; Agtr 1; Agtr1; AGTR1_HUMAN; Agtr1a; AGTR1B; Ang II; Angiotensin II receptor type 1; Angiotensin II type 1 receptor; Angiotensin II type-1 receptor; Angiotensin receptor 1; Angiotensin receptor 1B; AT 1B; AT 1r; AT-1B; AT-1r; AT1; At1a; AT1AR; AT1B; AT1BR; AT1R; AT2R1; AT2R1A; AT2R1B; HAT1R; Type 1 angiotensin II receptor; Type 1B angiotensin II receptor; Type-1 angiotensin II receptor.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human AT2R C-terminus.

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Predicted Molecular Weight: 41kDa.

Storage:

Anti-AT2R抗體Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Anti-AT2R抗體WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.kl116Si01 調(diào)節(jié)激活正常T-細胞表達分泌因子(RANTES)多克隆抗體 Polyclonal Antibody to Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
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kl116Bo01 調(diào)節(jié)激活正常T-細胞表達分泌因子(RANTES)多克隆抗體 Polyclonal Antibody to Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES)
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kl592Ra01 生長抑素(SST)多克隆抗體 Polyclonal Antibody to Somatostatin (SST)
kl592Po01 生長抑素(SST)多克隆抗體 Polyclonal Antibody to Somatostatin (SST)

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產(chǎn)品名稱：Anti-AT2R抗體